When using for initial cleanse you should take 4 Oxy-Powder capsules with a full glass of purified water on an empty stomach before bed. If you do not achieve 3-5 bowel movements the next day, increase serving size by 2 capsules each night until you achieve 3-5 movements. Continue this amount for 5 more days. After the 5 days are up you should take a maintenance dose of either 1 capsule per day OR the dose you use in the initial phase 2-3 times per week.